![]() ![]() With continued releases of the OX5034 males throughout the mosquito season, the absence of female mosquitoes emerging in the release area results in mosquito population decline. OX5034 males carry a gene (tTAV-OX5034) that is passed on to their offspring and that allows their male offspring to survive while their female offspring do not. How does the technology result in mosquito population decline? These communities could be at higher risk for exposure to mosquitoes, virus transmission, and exposure to pesticides from mosquito control. This may be especially beneficial for densely populated communities with environmental justice concerns. Additionally, the use of modified mosquitoes could reduce the use of chemical pesticides for mosquito control. Aedes aegypti mosquitoes, which is an invasive mosquito species in the United States, can transmit diseases such as dengue, Zika, and chikungunya to humans therefore, mosquito control is important for protecting human health. Oxitec’s Experimental Use Permit (EUP) will gather data to determine whether OX5034 mosquitoes are effective at reducing the number of Aedes aegypti mosquitoes before the company decides whether to apply for a geographically broader or nationwide FIFRA registration. Oxitec developed genetically engineered Aedes aegypti (OX5034) mosquitoes that are intended to reduce the local mosquito population. Genetically Modified Male Mosquitoes Developed by Oxitec What is the purpose of Oxitec's Experimental Use Permit? Wolbachia Mosquitoes Developed by MosquitoMate.Genetically modified male mosquitoes developed by Oxitec.To learn more about each technology, read the Q&A section below. Additionally, for both technologies, the pesticidal activity is species specific which limits the impact to non target organisms. The male mosquitoes pass along traits that do not allow female offspring to survive therefore, recurrent release of male mosquitoes result in fewer offspring and consequently, population decline. Both mosquito technologies introduce modified male mosquitoes, which do not bite humans, into wild populations to mate with females that are already present in the are. ![]() One Experimental Use Permit (including one product amendment and extension) has been issued.Īlthough these technologies user different methods to modify mosquitoes, the technologies share several similarities. Modified male mosquitoes carry a gene that results in female offspring not surviving.Several Experimental Use Permits and one registration have been issued. Wolbachia are naturally occurring bacteria that are used to infect mosquitoes to reduce mosquito population.Since 2012, EPA has evaluated several emerging mosquito population control technologies, which are based on two different different approaches: Some mosquito technologies, which modify mosquitoes to prevent female offspring from survive to adulthood, have the potential to reduce mosquito populations and the use of traditional mosquito products. Traditionally, mosquitoes have been managed with conventional adulticides and larvicides however, as technology advances, companies are discovering innovative ways to control mosquito populations. ![]()
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